The problem

In the context of many clinical trials, particularly phase III, researchers are interested in comparing the two, under evaluation, treatments, in terms of the response rate, both complete and partial, after a certain period of time. For example, in the context of these studies, healthcare professionals record for each participant whether, after a certain period of administration of each treatment, they show: complete response (CR), partial response (PR) or progression of the disease (Progression of Disease-PD), and then compare the treatments under investigation, in terms of the rate of overall response that occurred (CR and PR).

The purpose

Indication of the most effective treatment in terms of overall response rate (CR and PR).

The solution

By using the appropriate statistical methodology (Pearson chi-square test, Fisher's exact test) and after the test of the assumptions, a comparison will be made between the two or more compared treatments, in order to enable the user to evaluate which of the under investigation treatments are more effective in terms of overall response rate (CR and PR).

The benefit

Healthcare professionals will be able to easily, quickly and without prior statistical knowledge, evaluate the effectiveness of a treatment they are interested in, in terms of the overall response rate (CR and PR).